"OpsMgr Management Configuration" event ID 29181 on all SCOM 2012 R2 Management Servers

The details suggest the following... any suggestions?

OpsMgr Management Configuration Service failed to execute 'LocalHealthServiceDirtyNotification' engine work item due to the following exception

Microsoft.EnterpriseManagement.ManagementConfiguration.DataAccessLayer.DataAccessOperationTimeoutException: Exception of type 'Microsoft.EnterpriseManagement.ManagementConfiguration.DataAccessLayer.DataAccessOperationTimeoutException' was thrown.
   at Microsoft.EnterpriseManagement.ManagementConfiguration.DataAccessLayer.DataAccessOperation.ExecuteSynchronously(Int32 timeoutSeconds, WaitHandle stopWaitHandle)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.SqlConfigurationStore.ConfigurationStore.ExecuteOperationSynchronously(IDataAccessConnectedOperation operation, String operationName)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.SqlConfigurationStore.ConfigurationStore.IsAgentDirty(Guid agentId, LastAgentChangeCookie& lastAgentChangeCookie)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.Engine.LocalDirtyNotificationWorkItem.ExecuteWorkItem()
   at Microsoft.EnterpriseManagement.ManagementConfiguration.Interop.ConfigServiceEngineWorkItem.Execute()

In addition I am also seeing Event ID 29120 with the following details...

OpsMgr Management Configuration Service failed to process configuration request (Xml configuration file or management pack request) due to the following exception

Microsoft.EnterpriseManagement.ManagementConfiguration.DataAccessLayer.DataAccessException: Data access operation failed
   at Microsoft.EnterpriseManagement.ManagementConfiguration.DataAccessLayer.DataAccessOperation.ExecuteSynchronously(Int32 timeoutSeconds, WaitHandle stopWaitHandle)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.SqlConfigurationStore.ConfigurationStore.ExecuteOperationSynchronously(IDataAccessConnectedOperation operation, String operationName)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.SqlConfigurationStore.ConfigurationStore.GetConfiguration(IDictionary`2 agentList, ConfigurationSignature configurationSignature)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.Engine.AgentRequestProcessor.ProcessConfigurationRequest(ICollection`1 requestList, Int32& processedRequestsCount)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.Engine.AgentRequestProcessor.Execute()
   at Microsoft.EnterpriseManagement.ManagementConfiguration.Engine.ThreadManager.ResponseThreadStart(Object state)
-----------------------------------
System.Data.SqlClient.SqlException (0x80131904): Timeout expired.  The timeout period elapsed prior to completion of the operation or the server is not responding.
   at System.Data.SqlClient.SqlConnection.OnError(SqlException exception, Boolean breakConnection)
   at System.Data.SqlClient.TdsParser.ThrowExceptionAndWarning()
   at System.Data.SqlClient.TdsParser.Run(RunBehavior runBehavior, SqlCommand cmdHandler, SqlDataReader dataStream, BulkCopySimpleResultSet bulkCopyHandler, TdsParserStateObject stateObj)
   at System.Data.SqlClient.SqlDataReader.ReadInternal(Boolean setTimeout)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.SqlConfigurationStore.AgentConfigGetOperation.ReadChildrenAgentInfo(IDataReader reader, AgentConfigurationBuilder builder)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.SqlConfigurationStore.AgentConfigGetOperation.ReadData(SqlDataReader reader)
   at Microsoft.EnterpriseManagement.ManagementConfiguration.DataAccessLayer.ReaderSqlCommandOperation.SqlCommandCompleted(IAsyncResult asyncResult)